产品货号：
Z13993
中文名称：
Connexin-26/GJB2抗体
英文名称：
Anti-Connexin-26/GJB2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Connexin-26/GJB2 Antibody |
| 指标别名 | Connexin 26;Connexin-26;CX26;DFNA3;DFNA3A;DFNB1;DFNB1A;Gap junction beta 2 protein;GJB2;HID;KID;NSRD1;PPK |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | GJB2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human GJB2(1-16aa,MDWGTLQTILGGVNKH),different from the related mouse and rat sequences by two amino acids. |
| 实际分子量 | 26KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Connexin26(CX26),also known as GAP junction protein,beta2,GJB2.Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells.These structures were shown to consist of cell-to-cell channels.Proteins,called connexins,purified from fractions of enriched gap junctions from different tissues differ.The 3-prime untranslated region of the CX26 transcript contains a putative mRNA instability sequence.The deduced 226-amino acid protein has a calculated molecular mass of about 26kD.CX26 shares 92.5% identity with rat Cx26.connexin 26(GJB2) is assigned to human chromosome 13q11-q12.Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response.Connexin 26 gene(GJB2) mutation modulates the severity of hearing loss associated with the 1555A-G mitochondrial mutation. |
| Uniprot ID | P29033 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | gap junction protein,beta 2,26kDa |
| 蛋白名全称 | Gap junction beta-2 protein |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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